Malleable machines take shape in eukaryotic transcriptional regulation
نویسندگان
چکیده
منابع مشابه
Malleable machines take shape in eukaryotic transcriptional regulation.
Transcriptional control requires the spatially and temporally coordinated action of many macromolecular complexes. Chromosomal proteins, transcription factors, co-activators and components of the general transcription machinery, including RNA polymerases, often use structurally or stoichiometrically ill-defined regions for interactions that convey regulatory information in processes ranging fro...
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Understanding ribosomal protein gene regulation provides a good avenue for understanding gene regulatory networks. Even after 5 decades of research on ribosomal protein gene regulation, little is known about how higher eukaryotic ribosomal protein genes are coordinately regulated at the transcriptional level. However, a few recent papers shed some light on this complicated problem.
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ژورنال
عنوان ژورنال: Nature Chemical Biology
سال: 2008
ISSN: 1552-4450,1552-4469
DOI: 10.1038/nchembio.127